EEG Variabilities in Diagnosis of Schizophrenia, Bipolar Disorder, and PTSD: A Literature Review
DOI:
https://doi.org/10.5281/zenodo.10214265Keywords:
eeg, ptsd, schizophrenia, bipolar disorders, psychiatryAbstract
Clinically significant disturbances in a person's cognition, emotional regulation, or behavior are the hallmarks of mental health disorders, which are debilitating psychiatric conditions. This review is being conducted to investigate whether the present literature regarding electroencephalography (EEG) patterns in individuals diagnosed with either schizophrenia, bipolar disorder (BD), or post-traumatic disorder (PTSD) show diagnostic biomarkers of the aforementioned mental health (MH) disorders. While the data from selected studies reported a relative level of variation, EEG activity and asymmetry were suggested in specific brain areas that potentially correlate with these MH disorders.
Mean synchronization in the alpha band decreased in BD patients, with the most significant decreases in fronto-central and centro-parietal connections. Furthermore, BD patients' clustering coefficient and global efficiency decreased, whereas the characteristic path length increased. Although the studies emphasizing the relationship between PTSD and EEG all pinpoint brain areas of increased activation in individuals diagnosed with PTSD, there is variation between specific areas of interest: the left frontal lobe, right frontal lobe, and the centro-parietal lobe. Despite the complexity of the MH disorder, abnormal EEG patterns found in schizophrenic patients have been shown across studies that demonstrate elevations of slow wave activity and deficits in alpha band frequency.
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